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Publications

Coetzee Laboratory

Selected Publications

For a full list of Dr. Coetzee’s publications, please visit his Google Scholar page.

Coetzee SG, Pierce S, Brundin P, Brundin L, Hazelett DJ, Coetzee GA. In press. Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiology. Sci Rep.       Article

Coetzee SG, Coetzee GA, Hazelett DJ. 2015. motifbreakR: an R/Bioconductor package for predicting the disruptiveness of single nucleotide polymorphisms or mutations on transcription factor binding sites. Bioinformatics 31(23):3847–3849.       PubMed        Article

Han YY, Hazelett DJ, Wicklund F, Frederick R, Schumacher RF, Stram DO, Berndt SI, Wang Z, Rand KA, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Xu J, Travis RC, Key TJ, Siddiq A, Canzian F, Takahashi A, Kubo M, Stanford JL, Kolb S, Gapstur SM, Diver RW, Stevens VL, Strom SS, Pettaway CA, Al Olama AA, Kote-Jarai Z, Eeles RA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, Isaacs WB, Chen C, Lindstrom S, Le Marchand L, Giovannucci EL, Pomerantz M, Long H, Li F, Ma J, Stampfer M, John EM, Ingles SA, Kittles RA, Murphy AB, Blot WJ, Signorello LB, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske MC, Wu S-Y, Hennis AJM, Rybicki BA, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Riboli E, Li Q, Freedman ML, Hunter DJ, Gronberg H, Cook MB, Nakagawa H, Kraft P, Chanock SJ,  Easton DF, Henderson BE, Coetzee GA, Conti DV, Haiman CA. 2015. Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. Hum Mol Genet 24(19):5603–5618        PubMed

Amin Al Olama et al …. Coetzee GA, Eeles RA, Kote-Jarai Z. 2015. Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans. Hum Mol Genet 24(19):5589–5602            PubMed

Hazelett DJ, Rhie SK, Gaddis M, Yan C, Lakeland DL, Coetzee SG, Henderson BE, Noushmehr H, Cozen W, Kote-Jarai Z, Eeles RA, Easton DF, Haiman CA, Lu W, Farnham PJ, Coetzee GA. 2014. Comprehensive functional annotation of 77 prostate cancer risk loci. PLoS Genet 10(1):e1004102              PubMed

Noushmehr H, Coetzee SG, Rhie S, Yan C, Coetzee GA. The functionality of prostate cancer predisposition risk regions is revealed by AR enhancers. In: Wang Z, editor. Androgen-responsive genes in prostate cancer. New York (NY): Springer US; c2013. p. 59–84.   Article

Coetzee SG, Rhie SK, Berman BP, Coetzee GA, Noushmehr H. 2012. FunciSNP: an R/Bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs. Nucleic Acids Res 40(18):e139            PubMed

Coetzee GA. 2012. The usefulness of prostate cancer genome-wide association studies. J Urol 187(1):9–10.   Article

Freeman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG. 2011. Principles for post-GWAS functional characterization of cancer risk loci. Nat Genet 43(6):513–518       PubMed

Noushmehr H, Coetzee GA. 2011. Identification and functional annotation of GWAS risk SNPs. Cell Cycle 10(23):3995–3996.                PubMed

Jia L, Landan G, Pomerantz M, Jascheck R, Herman P, Reich D, Yan C, Khalid O, Kantoff P, Oh W, Manak JR, Berman BP, Henderson BE, Frenkel B, Haiman CA, Freedman M, Tanay A, Coetzee GA. 2009. Functional enhancers at the gene-poor 8q24 cancer-linked locus. PLoS Genet 5:e1000597                        PubMed

Jia L, Berman BP, Jariwala U, Yan X, Cogan JP, Walters A, Chen T, Buchanan G, Frenkel B, Coetzee GA. 2008. Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity. PLoS One 3(11):e3645   PubMed

Jia L, Shen HC, Wantroba M, Khalid M, Liang G, Wang Q, Gentzschein E, Pinski JK, Stanczyk FZ, Jones PA, Coetzee GA. 2006. Locus-wide chromatin remodeling and enhanced androgen receptor-mediated transcription in recurrent prostate tumor cells. Mol Cell Biol 26(19):7331–7341    PubMed

Jia L, Coetzee GA. 2005. AR-dependent PSA expression in androgen-independent prostate cancer does not involve AR occupancy of the PSA locus. Cancer Res 65(17):8003–8008          PubMed

Ingles SA, Ross RK, Yu MC, Irvine RA, La Pera G, Haile RW, Coetzee GA. 1997. Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor. J Natl Cancer Inst 89(2):166–170     PubMed

Irvine RA, Yu MC, Ross RK, Coetzee GA. 1995. The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer. Cancer Res 55(9):1937–1940. PubMed

Monroe KR, Yu MC, Kolonel LN, Coetzee GA, Wilkens LR, Ross RK, Henderson BE. 1995. Evidence of X-linked or recessive genetic component to prostate cancer risk. Nat Med:827–829       Article