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Publications

Coetzee Laboratory

Selected Publications

For a full list of Dr. Coetzee’s publications, please visit his Google Scholar page.

Buckley M, Woods NT, Tyrer JP, Mendoza-Fandiño G, Lawrenson K, Hazelett DJ, Najafabadi HS, Gjyshi A, Carvalho RS, Lyra Jr. PC, Coetzee SG, Shen HC, Karevan R, Yang A, Earp MA, Yoder SJ, Risch H, Chenevix-Trench G, Ramus SJ, Phelan CM, Coetzee GA, Noushmehr H, Hughes TR, Sellers TA, Goode EL, Pharoah PD, Gayther SA, Monteiro AN. 2018. Functional analysis and fine mapping of the 9p22.2 ovarian cancer susceptibility locus. Can Res.

Schmit SL*, Edlund CK*, Schumacher FR*, Gong J*,…Coetzee GA,…Peters U, Casey G, Hsu L, Conti DV, Gruber SB. 2018. Novel common genetic susceptibility loci for colorectal cancer. J Natl Cancer Inst.

Pierce SE, Tyson T, Booms A, Prahl J, Coetzee GA. 2018. Parkinson’s disease genetic risk in a midbrain neuronal line. Neurobiol Dis 114:53–64.

Coetzee GA, Pierce SE. 2018. The five dimensions of Parkinson’s disease genetic risk. J Parkinsons Dis 8:13–15.

Pierce SE, Coetzee GA. 2017. Parkinson’s disease-associated genetic variation is linked to quantitative expression of inflammatory genes. PLoS One 12(4):e0175882.

Feng Y*, Rhie SK*,…Coetzee GA…,Haiman CA. 2017. Characterizing genetic susceptibility to breast cancer in women of African ancestry. Cancer Epidemiol Biomarkers Prev 26(7):1016–1026.

Rhie SK, Guo Y, Tak YG, Yao L, Shen H, Coetzee GA, Laird PW, Farnham PJ. 2016. Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits. Epigenetics Chromatin 9:50.

Coetzee SG, Pierce SE, Brundin P, Brundin L, Hazelett DJ, Coetzee GA. 2016. Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiologySci Rep.       

Coetzee SG, Coetzee GA, Hazelett DJ. 2015. motifbreakR: an R/Bioconductor package for predicting the disruptiveness of single nucleotide polymorphisms or mutations on transcription factor binding sitesBioinformatics 31(23):3847–3849.       

Han YY, Hazelett DJ, Wicklund F, Frederick R, Schumacher RF, Stram DO, Berndt SI, Wang Z, Rand KA, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Xu J, Travis RC, Key TJ, Siddiq A, Canzian F, Takahashi A, Kubo M, Stanford JL, Kolb S, Gapstur SM, Diver RW, Stevens VL, Strom SS, Pettaway CA, Al Olama AA, Kote-Jarai Z, Eeles RA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, Isaacs WB, Chen C, Lindstrom S, Le Marchand L, Giovannucci EL, Pomerantz M, Long H, Li F, Ma J, Stampfer M, John EM, Ingles SA, Kittles RA, Murphy AB, Blot WJ, Signorello LB, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske MC, Wu S-Y, Hennis AJM, Rybicki BA, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Riboli E, Li Q, Freedman ML, Hunter DJ, Gronberg H, Cook MB, Nakagawa H, Kraft P, Chanock SJ,  Easton DF, Henderson BE, Coetzee GA, Conti DV, Haiman CA. 2015. Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regionsHum Mol Genet 24(19):5603–5618.        

Amin Al Olama et al …. Coetzee GA, Eeles RA, Kote-Jarai Z. 2015. Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among EuropeansHum Mol Genet 24(19):5589–5602.     

Hazelett DJ, Rhie SK, Gaddis M, Yan C, Lakeland DL, Coetzee SG, Henderson BE, Noushmehr H, Cozen W, Kote-Jarai Z, Eeles RA, Easton DF, Haiman CA, Lu W, Farnham PJ, Coetzee GA. 2014. Comprehensive functional annotation of 77 prostate cancer risk lociPLoS Genet 10(1):e1004102.         

Noushmehr H, Coetzee SG, Rhie S, Yan C, Coetzee GA. The functionality of prostate cancer predisposition risk regions is revealed by AR enhancers. In: Wang Z, editor. Androgen-responsive genes in prostate cancer. New York (NY): Springer US; c2013. p. 59–84.   

Coetzee SG, Rhie SK, Berman BP, Coetzee GA, Noushmehr H. 2012. FunciSNP: an R/Bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPsNucleic Acids Res 40(18):e139.          

Coetzee GA. 2012. The usefulness of prostate cancer genome-wide association studiesJ Urol 187(1):9–10.   

Freeman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG. 2011. Principles for post-GWAS functional characterization of cancer risk lociNat Genet 43(6):513–518.

Noushmehr H, Coetzee GA. 2011. Identification and functional annotation of GWAS risk SNPsCell Cycle 10(23):3995–3996.       

Jia L, Landan G, Pomerantz M, Jascheck R, Herman P, Reich D, Yan C, Khalid O, Kantoff P, Oh W, Manak JR, Berman BP, Henderson BE, Frenkel B, Haiman CA, Freedman M, Tanay A, Coetzee GA. 2009. Functional enhancers at the gene-poor 8q24 cancer-linked locusPLoS Genet 5:e1000597.                      

Jia L, Berman BP, Jariwala U, Yan X, Cogan JP, Walters A, Chen T, Buchanan G, Frenkel B, Coetzee GA. 2008. Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacityPLoS One 3(11):e3645.   

Jia L, Shen HC, Wantroba M, Khalid M, Liang G, Wang Q, Gentzschein E, Pinski JK, Stanczyk FZ, Jones PA, Coetzee GA. 2006. Locus-wide chromatin remodeling and enhanced androgen receptor-mediated transcription in recurrent prostate tumor cellsMol Cell Biol 26(19):7331–7341.  

Jia L, Coetzee GA. 2005. AR-dependent PSA expression in androgen-independent prostate cancer does not involve AR occupancy of the PSA locusCancer Res 65(17):8003–8008.   

Ingles SA, Ross RK, Yu MC, Irvine RA, La Pera G, Haile RW, Coetzee GA. 1997. Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptorJ Natl Cancer Inst 89(2):166–170.    

Irvine RA, Yu MC, Ross RK, Coetzee GA. 1995. The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancerCancer Res 55(9):1937–1940. 

Monroe KR, Yu MC, Kolonel LN, Coetzee GA, Wilkens LR, Ross RK, Henderson BE. 1995. Evidence of X-linked or recessive genetic component to prostate cancer riskNat Med 827–829.